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Genes, pX

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Definition: DNA sequences that form the coding region for at least three proteins which regulate the expression of HUMAN T-LYMPHOTROPIC VIRUS 1 and HUMAN T-LYMPHOTROPIC VIRUS 2. The proteins are p21(x), p27(rex), and p40(tax). The tax (trans-activator x) and rex (regulator x) genes are part of pX but are in overlapping reading frames. X was the original designation for the sequences or region (at that time of unknown function) in the long open reading frame (lor) which is now called pX.      Other names tax Genes; rex Genes; pX Genes; HTLV-II tax Genes; HTLV-II rex Genes; HTLV-I tax Genes; HTLV-I rex Genes; Genes, tax; Genes, rex; tax Genes, HTLV-II; tax Genes, HTLV-I; tax Gene, HTLV-II; tax Gene, HTLV-I; tax Gene; rex Genes, HTLV-II; rex Genes, HTLV-I; rex Gene, HTLV-II; rex Gene, HTLV-I; rex Gene; pX Gene
 
SubstanceCAS Registry & nameCategoriesSource
p12I protein, Human T-lymphotropic virus 1  0   *Viral Regulatory and Accessory Proteins Deltaretrovirus Antigens Genes, pX. J Virol 1993 Dec;67(12):7701-4
tof protein, Human T-lymphotropic virus 1  0   *Retroviridae Proteins Human T-lymphotropic virus 1 Genes, pX. J Virol 1992 Mar;66(3):1737-45
rof protein, Human T-lymphotropic virus 1  0   *Retroviridae Proteins Human T-lymphotropic virus 1 Genes, pX. J Virol 1992 Mar;66(3):1737-45

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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