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Amyloid beta-Protein Precursor

More information in Books or onNLM PubMed
Definition: A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES.     
Examples Amyloid beta-Peptides 		Other names beta-Protein Precursor, Amyloid; beta Amyloid Protein Precursor; Nexin II, Protease; Nexin 2, Protease; Amyloid beta Protein Precursor; Protease Nexin II; Protease Nexin 2; Amyloid beta Precursor Protein; beta-Amyloid Protein Precursor; Amyloid Protein Precursor; Amyloid A4 Protein Precursor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
APP protein, human  0   *Amyloid beta-Protein Precursor.
amyloid beta-protein precursor C-terminal fragment beta, human  0   *Peptide Fragments *Amyloid beta-Protein Precursor. J Neurosci Res 2003 Nov 1;74(3):386-92
APP170-188 peptide  0   *Peptide Fragments Amyloid beta-Protein Precursor. Chemistry. 2005 Jan 21;11(3):903-9
APP63-73  0   *Peptide Fragments *Amyloid beta-Protein Precursor. Neuroreport 2004 Dec 3;15(17):2677-80
Aplp2 protein, rat  0   *Nerve Tissue Proteins *Amyloid beta-Protein Precursor.
CTFgamma protein, human  0   *Peptide Fragments *Amyloid beta-Protein Precursor. Neurobiol Dis 2004 Nov;17(2):205-18
Aplp2 protein, mouse  0   *Amyloid beta-Protein Precursor. J Neurochem 2004 Oct;91(2):423-8
APLP1 protein, human  0   *Amyloid beta-Protein Precursor.
beta-sAPP protein, human  0   *Peptide Fragments *Amyloid beta-Protein Precursor. Exp Neurol. 2003 Sep;183(1):74-80
betaA4 amyloid precursor protein (139-157), human  0   *Peptide Fragments *Amyloid beta-Protein Precursor. J Neurochem 2003 May;85(3):709-16
amyloid beta-protein precursor 695 (319-339)  0   *Peptide Fragments *Amyloid beta-Protein Precursor. Neuroreport 2001 Oct 29;12(15):3317-9
amyloid precursor protein carboxyl-terminal fragment gamma  0   *Peptide Fragments *Amyloid beta-Protein Precursor. J Biol Chem 2001 Nov 23;276(47):43756-60
CTFgamma protein, rat  0   *Peptide Fragments *Amyloid beta-Protein Precursor Membrane Proteins. J Biol Chem 2001 Sep 21;276(38):35235-8
amyloid beta-protein precursor CT105  0   *Peptide Fragments *Amyloid beta-Protein Precursor. J Neurosci Res 2000 May 15;60(4):565-70
SPA4CT protein, recombinant  0   *Peptide Fragments *Recombinant Proteins *Amyloid beta-Protein Precursor Membrane Proteins Protein Sorting Signals. FEBS Lett 1999 Jun 25;453(3):288-92
amyloid beta-protein precursor 770 (713-730)  0   *Peptide Fragments *Amyloid beta-Protein Precursor. Am J Pathol 1999 Apr;154(4):1001-7
amyloid beta-protein precursor inhibitor  0   *Proteins Amyloid beta-Protein Precursor/antagonists & inhibitors. Proteins 1999 Mar 1;34(4):520-32
amyloid protein precursor-binding protein 1, human  0   *DNA-Binding Proteins Amyloid beta-Protein Precursor. J Biol Chem 1996 May 10;271(19):11339-46
alpha-sAPP protein, human  0   *Peptide Fragments *Amyloid beta-Protein Precursor. Nat Med 1995 Aug;1(8):829-32
APP717  0   *Amyloid beta-Protein Precursor Mutation. Neurosci Lett 1991 Aug 5;129(1):134-5
amyloid beta-protein precursor 770 (681-695)  0   *Peptide Fragments *Amyloid beta-Protein Precursor. Tohoku J Exp Med 1994 Nov;174(3):189-98
amyloid beta-protein precursor 695 (681-695)  0   *Peptide Fragments *Amyloid beta-Protein Precursor. Tohoku J Exp Med 1994 Nov;174(3):189-98
amyloid beta-protein precursor 695 (18-38)  0   *Peptide Fragments *Amyloid beta-Protein Precursor. Tohoku J Exp Med 1994 Nov;174(3):189-98
amyloid beta-protein precursor 770 (301-323)  0   *Peptide Fragments *Amyloid beta-Protein Precursor. Tohoku J Exp Med 1994 Nov;174(3):181-7
appican  0   *Proteoglycans *Amyloid beta-Protein Precursor Alzheimer Disease. J Biol Chem 1995 May 19;270(20):11839-44
amyloid precursor protein, carboxy-terminal 100 residues  0   *Peptide Fragments *Amyloid beta-Protein Precursor. Neurosci Lett 1994 Oct 24;180(2):151-4
APLP2 protein, human  0   *Nerve Tissue Proteins *Amyloid beta-Protein Precursor Alzheimer Disease. Nat Genet 1993 Sep;5(1):95-100; Proc Natl Acad Sci USA 1990;87(7):2405
Aplp1 protein, mouse  0   *Amyloid beta-Protein Precursor. Proc Natl Acad Sci U S A 1992 Nov 15;89(22):10758-62

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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