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Talin

More information in Books or onNLM PubMed
Definition: A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS; VINCULIN; and ACTINS and appears to participate in generating a transmembrane connection between the extracellular matrix and the cytoskeleton.  a cytoplasmic protein; /drug eff /ultrastruct permitted    Other names Protein, Band 2; Protein p235, Platelet; Platelet Protein p235; Band 2 Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TLN2 protein, mouse  0   *Talin. Cell Motil Cytoskeleton 2007 Mar;64(3):157-73
TLN1 protein, human  0   *Talin. Cell Motil Cytoskeleton 2007 Mar;64(3):157-73
talin protein, mouse  0   *Talin. Nature 1990 Oct 18;347(6294):685-9
TLN2 protein, human  0   *Talin. Biochem Biophys Res Commun 2001 Sep 7;286(5):880-5

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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