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Primary Ovarian Insufficiency

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Definition: Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections.     
See Also Menopause, Premature 		Other names Resistant Ovary Syndrome; Ovarian Failure, Premature; Gonadotropin-Resistant Ovary Syndrome; Resistant Ovary Syndromes; Primary Ovarian Insufficiencies; Premature Ovarian Failures; Ovary Syndromes, Resistant; Ovary Syndromes, Gonadotropin-Resistant; Ovary Syndrome, Resistant; Ovary Syndrome, Gonadotropin-Resistant; Ovarian Insufficiency, Primary; Ovarian Insufficiencies, Primary; Ovarian Failures, Premature; Insufficiency, Primary Ovarian; Insufficiencies, Primary Ovarian; Gonadotropin-Resistant Ovary Syndromes; Gonadotropin Resistant Ovary Syndrome; Premature Ovarian Failure
 
SubstanceCAS Registry & nameCategoriesSource
Osteosclerosis with ichthyosis and premature ovarian failure  0   *Bone Diseases, Developmental *Sclerosis *Ichthyosis Vulgaris *Primary Ovarian Insufficiency.
Premature ovarian failure, familial  0   *Primary Ovarian Insufficiency.

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