Definition: Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-related transcriptional control. c-fos combines with c-jun (PROTO-ONCOGENE PROTEINS C-JUN) to form a c-fos/c-jun heterodimer (TRANSCRIPTION FACTOR AP-1) that binds to the TRE (TPA-responsive element) in promoters of certain genes.
Other names p55(c-fos); fos Proto-Oncogene Proteins; c-fos Proteins; Fos-Related Antigens; Fos B Protein; p55 c fos; fos Proto Oncogene Proteins; c fos Proteins; Proto Oncogene Proteins fos; Proto Oncogene Proteins c fos; Proto Oncogene Products c fos; Fos Related Antigens; p55 c-fos; Proto-Oncogene Proteins fos; Proto-Oncogene Products c-fos; Antigens, Fos-Related; FRAs