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Genes, fos

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Definition: Retrovirus-associated DNA sequences (fos) originally isolated from the Finkel-Biskis-Jinkins (FBJ-MSV) and Finkel-Biskis-Reilly (FBR-MSV) murine sarcoma viruses. The proto-oncogene protein c-fos codes for a nuclear protein which is involved in growth-related transcriptional control. The insertion of c-fos into FBJ-MSV or FBR-MSV induces osteogenic sarcomas in mice. The human c-fos gene is located at 14q21-31 on the long arm of chromosome 14.  fos stands for "Finkel" & "Osteogenic Sarcoma"   
See Also Oncogene Proteins v-fos; Proto-Oncogene Proteins c-fos 		Other names v-fos Genes; fos Genes; c-fos Genes; v-fos Oncogene; v-fos Gene; v fos Oncogenes; v fos Genes; fos Gene; c-fos Proto-Oncogene; c-fos Gene; c fos Proto Oncogenes; c fos Genes; v-fos Oncogenes; c-fos Proto-Oncogenes

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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