encyclopedia of medical concepts
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Interferon-beta
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Definition
: One of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and immunomodulating activity.
Pharmacological Action
Antineoplastic Agents
;
Antiviral Agents
;
Immunologic Factors
Other names
beta-
Interferon; Interferon, Fibroblast; beta Interferon; beta 1 Interferon; Interferon-
beta Biosyn Brand; Interferon, beta 1; Interferon beta1; Interferon beta; Fibroblast Interferon; Biosyn Brand of Interferon beta; beta-
1 Interferon; Interferon-
beta1; Interferon, beta-
1; Interferon, beta; Fiblaferon; Biosyn Brand of Interferon-
beta
Substance
CAS Registry & name
Categories
Source
Drugs
*
glycosylated recombinant human INF-
beta
0
*Interferon-beta.
Clin Cancer Res 1997 Apr;3(34):381-7
interferon beta 1a
145258-61-3
*Interferon-beta.
Pharma Action
Adjuvants, Immunologic
;
Antineoplastic Agents
Clin Pharmacol Ther 1994 Apr;55(4):478-80
AVONEX
;
REBIF
interferon beta-
1b
145155-23-3
*Interferon-beta
Recombinant Proteins.
Pharma Action
Adjuvants, Immunologic
Mol Cell Biol 1984;4(12):2745
BETASERON
;
EXTAVIA