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Clarithromycin

More information in Books or onNLM PubMed
Definition: A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit protein synthesis in bacteria by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.     
Pharmacological Action Anti-Bacterial Agents; Protein Synthesis Inhibitors 		Other names TE031; TE 031; A56268; A 56268; TE-031; Biaxin; A-56268; 6-O-MethylerythromycinDrugs* : BIAXIN; BIAXIN XL; CLARITHROMYCIN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
14-R-hydroxy-clarithromycin  0   Clarithromycin/*analogs & derivatives. Jpn J Antibiot. 2004 Feb;57(1):124-33
14-hydroxyclarithromycin  110671-78-8 Erythromycin, 14-hydroxy-6-O-methyl  Clarithromycin/*analogs & derivatives. Eur J Clin Microbiol Infect Dis 1988;(7)1:73
6,11-di-O-methylerythromycin A  0   Clarithromycin/*analogs & derivatives. J Antibiot (Tokyo) 1984;37(2):187

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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