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8-Hydroxy-2-(di-n-propylamino)tetralin

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Definition: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.     
Pharmacological Action Serotonin Receptor Agonists 		Other names 8-OH-DPAT; 8-Hydroxy-2-(di-n-propylamino)tetralin, (S)-Isomer; 8-Hydroxy-2-(di-n-propylamino)tetralin, (R)-Isomer; 8-Hydroxy-2-(di-n-propylamino)tetralin, (+-)-Isome; 8-Hydroxy-2-(di-n-propylamino)tetralin Hydrochlori; 8-Hydroxy-2-(di-n-propylamino)tetralin Hydrochlori; 8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromid; 8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromid; 8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromid; 8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromid
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-methyl-8-hydroxy-2-(di-n-propylamino)tetralin  0   8-Hydroxy-2-(di-n-propylamino)tetralin/*analogs & derivatives Stereoisomerism. Eur J Pharmacol 1998 Apr 17;347(1):41-9
U 89968E  0   8-Hydroxy-2-(di-n-propylamino)tetralin/*analogs & derivatives. J Pharm Biomed Anal 1997 Mar;15(6):739-48
8-(((trifluoromethyl)sulfonyl)oxy)-2-(n-propylamino)tetralin  161970-95-2   8-Hydroxy-2-(di-n-propylamino)tetralin/*analogs & derivatives. Eur J Pharmacol 1996 Feb 22;297(3):205-11
UH 301  127126-21-0   8-Hydroxy-2-(di-n-propylamino)tetralin/*analogs & derivatives.
Pharma Action Serotonin Antagonists 		J Med Chem 1990;33(6):1541
8-hydroxy-1-methyl-2-(di-n-propylamino)tetralin  110312-35-1   8-Hydroxy-2-(di-n-propylamino)tetralin/*analogs & derivatives. J Med Chem 1987;30(11):2105
5-hydroxy-2-methyl-2-(di-n-propylamino)tetralin  85592-61-6   8-Hydroxy-2-(di-n-propylamino)tetralin/*analogs & derivatives. Acta Pharm Suec 1985;22(2):65
5-hydroxy-1-methyl-2-(di-n-propylamino)tetralin  96148-66-2   8-Hydroxy-2-(di-n-propylamino)tetralin/*analogs & derivatives. J Med Chem 1985;28(8):1049
UH 232  95999-11-4   8-Hydroxy-2-(di-n-propylamino)tetralin/*analogs & derivatives.
Pharma Action Dopamine Antagonists 		J Med Chem 1985;28(8):1049
8-methoxy-2-(di-n-propylamino)tetralin  3897-94-7 2-Naphthalenamine, 1,2,3,4-tetrahydro-8-methoxy-N,N-dipropyl  8-Hydroxy-2-(di-n-propylamino)tetralin/*analogs & derivatives. Pharmacol Biochem Behav 1981;15(5):785
5-hydroxy-2-N,N-dipropylaminotetralin  68593-96-4 1-Naphthalenol, 6-(dipropylamino)-5,6,7,8-tetrahydro  8-Hydroxy-2-(di-n-propylamino)tetralin/*analogs & derivatives. J Med Chem 19(4):547;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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