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Ribonucleoprotein, U1 Small Nuclear

More information in Books or onNLM PubMed
Definition: A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction.      Other names U1 snRNP; U1 Small Nuclear Ribonucleoproteins; Small Nuclear Ribonucleoproteins, U1; Ribonucleoproteins, Small, U1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
U1-C protein, human  0   *Ribonucleoprotein, U1 Small Nuclear. Arthritis Rheum. 2010 Dec;62(12):3730-40
spliceosomal peptide P140  0   *Peptide Fragments Ribonucleoprotein, U1 Small Nuclear. Arthritis Rheum 2008 Dec;58(12):3873-83
Snu56 protein, S cerevisiae  0   *Ribonucleoprotein, U1 Small Nuclear *Saccharomyces cerevisiae Proteins Protein Subunits. Mol Cell Biol 2008 Apr;28(8):2497-508
CG7564 protein, Drosophila  0   *Ribonucleoprotein, U1 Small Nuclear RNA Splicing Protein Subunits. Mol Cell Biochem 2008 Jan;307(1-2):177-83
U1-70K protein, Drosophila  0   *Ribonucleoprotein, U1 Small Nuclear *Drosophila Proteins. Genetics 2004 Dec;168(4):2059-65
SNRNP70 protein, human  0   *Ribonucleoprotein, U1 Small Nuclear RNA Splicing.
Snrnp70 protein, mouse  0   *Ribonucleoprotein, U1 Small Nuclear RNA Splicing.
Prp40 protein, S cerevisiae  0   *Ribonucleoprotein, U1 Small Nuclear *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1996 Mar;16(3):960-7
SNP1 protein, S cerevisiae  0   *Ribonucleoprotein, U1 Small Nuclear *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1995 Nov;15(11):6341-50
snf protein, Drosophila  0   *Ribonucleoprotein, U1 Small Nuclear *Drosophila Proteins. Genes Dev 1994 Apr 15;8(8):914-25
Prp39 protein, S cerevisiae  0   *Ribonucleoprotein, U1 Small Nuclear *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1994 Jun;14(6):3623-33
U1A protein  0   *Ribonucleoprotein, U1 Small Nuclear Saccharomyces cerevisiae Proteins. J Cell Biol 1992 Jul;118(1):11-21

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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