Definition: The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)
/biosyn /physiol permitted; DF: note short X ref
Other names LTC4; Leukotriene C 4; Leukotriene C 1; Leukotrienes C; Leukotriene C1; Leukotriene C-4; Leukotriene C-1; Leukotriene C