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Antigens, CD80

More information in Books or onNLM PubMed
Definition: A costimulatory ligand expressed by ANTIGEN-PRESENTING CELLS that binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.      Other names CD80 Antigens; B7-1 Costimulatory Molecule; B-Cell Activation Antigen; Ligand, B7-1; Costimulatory Molecule, B7-1; B7 1 Ligand; B7 1 Costimulatory Molecule; B7 1 Antigen; B Cell Activation Antigen; Antigen, B7 1; CD80 Antigen; B7-1 Ligand; B7-1 Antigen; Antigen, B7-1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CD80-CAP  0   *Oligopeptides Antigens, CD80. Inflamm Bowel Dis 2008 Apr;14(4):458-70
B-G antigen, Gallus gallus  0   *Proteins Antigens, CD80. Protein Sci 1994 Aug;3(8):1341-3

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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