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Centrosome

More information in Books or onNLM PubMed
Definition: The cell center, consisting of a pair of CENTRIOLES surrounded by a cloud of amorphous material called the pericentriolar region. During interphase, the centrosome nucleates microtubule outgrowth. The centrosome duplicates and, during mitosis, separates to form the two poles of the mitotic spindle (MITOTIC SPINDLE APPARATUS).     
Examples Centrioles 		Other names Pericentriolar Region; Regions, Pericentriolar; Region, Pericentriolar; Pericentriolar Regions; Centrosomes
 
SubstanceCAS Registry & nameCategoriesSource
pcm-1 protein, Xenopus  0   *Cell Cycle Proteins *Xenopus Proteins Centrosome.
Cetn3 protein, mouse  0   *Calcium-Binding Proteins Centrosome.
CP110 protein, human  0   *Microtubule-Associated Proteins *Phosphoproteins *Cell Cycle Proteins Centrosome. Dev Cell 2002 Sep;3(3):339-50
RABGAP1 protein, human  0   *Microtubule-Associated Proteins *GTPase-Activating Proteins Centrosome. EMBO J 1999 Apr 1;18(7):1772-82
Cep250 protein, human  0   *Autoantigens *Cell Cycle Proteins Centrosome. Arthritis Rheum 1998 Mar;41(3):551-8
CETN3 protein, human  0   *Calcium-Binding Proteins Centrosome. Proc Natl Acad Sci U S A 1997 Aug 19;94(17):9141-6
PCM1 protein, human  0   *Autoantigens *Cell Cycle Proteins Centrosome. J Cell Biol 1994 Mar;124(5):783-93

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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