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beta-Lactam Resistance

More information in Books or onNLM PubMed
Definition: Nonsusceptibility of bacteria to the action of the beta-lactam antibiotics. Mechanisms responsible for beta-lactam resistance may be degradation of antibiotics by BETA-LACTAMASES, failure of antibiotics to penetrate, or low-affinity binding of antibiotics to targets.  GEN or unspecified; prefer specifics   
Examples Cephalosporin Resistance; Penicillin Resistance 		Other names beta-Lactam Resistances; beta Lactam Resistance
 
SubstanceCAS Registry & nameCategoriesSource
DacD protein, E coli  0   *Escherichia coli Proteins beta-Lactam Resistance. Microbiology. 2011 Sep;157(Pt 9):2702-7
PBP5 protein, E coli  0   *Escherichia coli Proteins beta-Lactam Resistance. Microbiology. 2011 Sep;157(Pt 9):2702-7
PBP6 protein, E coli  0   *Escherichia coli Proteins beta-Lactam Resistance. Microbiology. 2011 Sep;157(Pt 9):2702-7
benzo(b)thiophene-2-boronic acid  0   *Boronic Acids *Thiophenes beta-Lactamases/antagonists & inhibitors beta-Lactam Resistance. J Med Chem 1998 Nov 5;41(23):4577-86
CmcT protein, Nocardia lactamdurans  0   *Bacterial Proteins *Membrane Proteins beta-Lactam Resistance. Microbiologia 1994 Mar-Jun;10(1-2):49-56

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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