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Genes, erbB-2

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Definition: The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythroblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.  in titles & translations spell as erbB-2; GENES, ERBB-1 is also available   
See Also Oncogene Proteins v-erbB; Receptor, Epidermal Growth Factor; Receptor, erbB-2 		Other names neu Genes; neu Gene; erbb2 Genes; erbb2 Gene; erbB-2 Gene; erbB 2 Genes; c-erbB-2 Proto-Oncogene; c-erbB-2 Gene; c erbB 2 Proto Oncogenes; c erbB 2 Genes; HER2 Genes; HER2 Gene; HER-2 Genes; HER-2 Gene; Gene, erbb2; Gene, HER2; c-erbB-2 Proto-Oncogenes; Genes, erbb2; Genes, HER2; erbB-2 Genes

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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