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Antigens, CD18

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Definition: Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the CD11 family of leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE-ADHESION). A defect in the gene encoding CD18 causes LEUKOCYTE-ADHESION DEFICIENCY SYNDROME.     
See Also Integrin alphaXbeta2; Leukocyte-Adhesion Deficiency Syndrome; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen 		Other names p150,95 beta Subunit; beta2, Integrin; beta-Subunit, p150,95; Integrin, beta2; p150,95 beta-Subunit; beta2 Integrin; CD18 Antigen; Integrin beta2; CD18 Antigens

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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