Endopeptidase K (definition)

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ψ ψ	Endopeptidase K

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Definition: An enzyme that catalyzes the hydrolysis of keratin, and of other proteins with subtilisin-like specificity. It hydrolyses peptide amides. Endopeptidase K is from the mold Tritirachium album Limber. (Enzyme Nomenclature, 1992) EC 3.4.21.64.

Other names Proteinase, Tritirachium Alkaline; Alkaline Proteinase, Tritirachium; Tritirachium Alkaline Proteinase; Protease K; Proteinase K

Substance	Categories	Source
methoxysuccinyl-alanyl-alanyl-alanyl-prolyl-phenylalanine chloromethyl ketone	*Amino Acid Chloromethyl Ketones Endopeptidase K/antagonists & inhibitors.	Bioorg Med Chem 2010 Dec 1;18(23):8383-7
methoxysuccinyl-alanyl-alanyl-alanyl-prolyl-valine chloromethyl ketone	*Amino Acid Chloromethyl Ketones Endopeptidase K/antagonists & inhibitors.	Bioorg Med Chem Lett 2010 May 1;20(9):2750-4
methoxysuccinyl-alanyl-alanyl-alanyl-prolyl-leucine chloromethyl ketone	*Amino Acid Chloromethyl Ketones Endopeptidase K/antagonists & inhibitors.	Bioorg Med Chem Lett 2010 May 1;20(9):2750-4
methoxysuccinyl-Ala-Ala-Pro-Phe-chloromethyl ketone	*Amino Acid Chloromethyl Ketones Endopeptidase K/antagonists & inhibitors.	Bioorg Med Chem Lett. 2009 Mar 1;19(5):1296-300

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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