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Macrophage Inflammatory Proteins

More information in Books or onNLM PubMed
Definition: Heparin-binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Originally identified as secretory products of MACROPHAGES, these chemokines are produced by a variety of cell types including NEUTROPHILS; FIBROBLASTS; and EPITHELIAL CELLS. They likely play a significant role in respiratory tract defenses.  DF: MACROPHAGE INFLAMM PROTEINS   
Examples Chemokine CCL3; Chemokine CCL4; Chemokine CCL19; Chemokine CCL20; Chemokine CXCL2 		Other names Inflammatory Proteins, Macrophage; Macrophage Inflammatory Protein-1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
aminooxypentane-MIP-1alphaP protein, human  0   *Macrophage Inflammatory Proteins. J Biol Chem 2000 Dec 15;275(50):30254-61
Nagrestipen  166089-33-4   *Macrophage Inflammatory Proteins. Clin Pharmacol Ther 1998 May;63(5):604-6
CCL15 protein, human  0   *Macrophage Inflammatory Proteins *Chemokines, CC. Eur J Biochem 1997 Sep 1;248(2):507-15; Proc Natl Acad Sci U S A 1998 May 26;95(11):6308-13
vMIP-1 protein, Human herpesvirus 8  0   *Viral Proteins Macrophage Inflammatory Proteins. Science 1997 Oct 10;278(5336):290-4
Ccl9 protein, mouse  0   *Macrophage Inflammatory Proteins *Chemokines, CC. J Immunol 1995 Sep 1;155(5):2661-7

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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