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Neopterin

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Definition: A pteridine derivative present in body fluids; elevated levels result from immune system activation, malignant disease, allograft rejection, and viral infections. (From Stedman, 26th ed) Neopterin also serves as a precursor in the biosynthesis of biopterin.      Other names Umanopterin; Neopterin, (threo-L)-Isomer; Neopterin, (threo-D)-Isomer; Neopterin, (erythro-L)-Isomer; Neopterin, (erythro-D)-Isomer; Neopterin, (R*, R*)-Isomer; Monapterin; 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridino
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
7,8-dihydroneopterin 2',3'-cyclic phosphate  0   Neopterin/*analogs & derivatives. J Bacteriol 1997 Aug;179(16):5165-70
neopterin-3'-triphosphate  35300-26-6 Triphosphoric acid, P-(3-(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)-2,3-dihydroxypropyl) ester, (S-(R*,S*))  *Neopterin. Biochem Biophys Res Commun 1988;152(3):1193
solfapterin  114312-02-6   *Aminoglycosides Neopterin/*analogs & derivatives. J Bacteriol 1988;170(3):1396
beta,gamma-methylene-7,8-dihydroneopterin 3'-triphosphate  92587-05-8 Isohypophosphoric acid, (phosphonomethyl)-, (S-(R*,S*))  Neopterin/*analogs & derivatives. Arch Biochem Biophys 1984;233(2):475
dihydroneopterin triphosphate  20574-65-6   Neopterin/*analogs & derivatives. J Biol Chem 251(21):6505;1976
neopterin 2',3'-cyclic phosphate  35068-28-1 4(1H)-Pteridinone, 2-amino-6-(hydroxy(2-hydroxy-1,3,2-dioxaphospholan-4-yl)methyl)-, P-oxide, (R-(R*,S*))  *Neopterin. Biochim Biophys Acta 302(1):222;1973
7,8-dihydroneopterin  1218-98-0 2-amino-7,8-dihydro-6-(1,2,3-trihydroxypropyl)-4(1H)-pteridinone  Neopterin/*analogs & derivatives. Free Radic Res 1995 Aug;23(2):123-36

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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