encyclopedia of medical concepts
ψ
ψ
ψ
Cromakalim
More information
in Books
or on
Definition
: A potassium-channel opening vasodilator that has been investigated in the management of hypertension. It has also been tried in patients with asthma. (Martindale, The Extra Pharmacopoeia, 30th ed, p352)
Pharmacological Action
Antihypertensive Agents
;
Bronchodilator Agents
;
Parasympatholytics
;
Vasodilator Agents
Other names
BRL38227; BRL38226; BRL 38227; BRL 38226; Lemakalim; Cromakalim, (trans)-
Isomer; Cromakalim, (3S-
trans)-
Isomer; Cromakalim, (3S-
cis)-
Isomer; Cromakalim, (3R-
trans)-
Isomer; Cromakalim, (3R-
cis)-
Isomer; BRL-
38227; BRL-
38226; BRL-
34915; Levcromakalim
Substance
CAS Registry & name
Categories
Source
Drugs
*
1-
(4-
(2-
ethoxy-
4-
methyl-
1H-
pyrrol-
1-
yl)-
3-
hydroxy-
2,2-
dimethylchroman-
6-
yl)-
3-
phenylurea
0
*Phenylurea Compounds
Cromakalim/*analogs & derivatives.
Int J Oncol. 2011 Dec;39(6):1609-17.
EMD 57970
0
Cromakalim/*analogs & derivatives.
J Biol Chem 1996 Apr 12;271(15):8796-9
EMD 60480
0
Cromakalim/*analogs & derivatives.
J Biol Chem 1996 Apr 12;271(15):8796-9
S 872342
0
Cromakalim/*analogs & derivatives.
Investig Urol (Berl) 1994;5:225-9
S 870121
0
Cromakalim/*analogs & derivatives.
Investig Urol (Berl) 1994;5:225-9