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Long Interspersed Nucleotide Elements

More information in Books or onNLM PubMed
Definition: Highly repeated sequences, 6K-8K base pairs in length, which contain RNA polymerase II promoters. They also have an open reading frame that is related to the reverse transcriptase of retroviruses but they do not contain LTRs (long terminal repeats). Copies of the LINE 1 (L1) family form about 15% of the human genome. The jockey elements of Drosophila are LINEs.      Other names Sequences, LINE Repeat; Sequence, LINE Repeat; Repeat Sequences, LINE; Repeat Sequence, LINE; LINE-1 Element; LINE Repeat Sequence; LINE 1 Elements; L1 Element; Jockey Element; Elements, LINE-1; Elements, L1; Elements, Jockey; Element, LINE-1; Element, L1; Element, Jockey; LINE Repeat Sequences; Long Interspersed DNA Sequence Elements; LINE-1 Elements; L1 Elements; Jockey Elements
 
SubstanceCAS Registry & nameCategoriesSource
Maui protein, Fugu rubripes  0   *Fish Proteins Long Interspersed Nucleotide Elements. Gene 1999 Feb 18;227(2):169-79
L1Hs-encoded protein p40, human  148349-28-4   *DNA-Binding Proteins DNA Transposable Elements Leucine Zippers Long Interspersed Nucleotide Elements. J Biol Chem 1992 Oct 5;267(28):19765-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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