encyclopedia of medical concepts
ψ 

Pinacidil

More information in Books or onNLM PubMed
Definition: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)     
Pharmacological Action Antihypertensive Agents; Membrane Transport Modulators; Vasodilator Agents 		Other names Anhydrous, Pinacidil; Pindac; Pinacidil AnhydrousDrugs* : PINDAC
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-(4-difluoromethoxyphenyl)-N'-pinacolyl-N''-cyanoguanidine  0   Pinacidil/*analogs & derivatives. Br J Pharmacol 2011 Feb;162(3):701-11
flokalin  0   Pinacidil/*analogs & derivatives. Fiziol Zh. 2005;51(6):18-24
Washington University solution  0   *Organ Preservation Solutions *Pinacidil. Ann Thorac Surg 2004 Aug;78(2):620-6
3-pyridyl pinacidil  60560-07-8   Pinacidil/*analogs & derivatives. J Cardiovasc Pharmacol 1993 Nov;22(5):731-43
pinacidil pyridine N-oxide  83285-82-9   Pinacidil/*analogs & derivatives. Br J Clin Pharmacol 1985;19(1):91

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy