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Brefeldin A

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Definition: A fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity.     
Pharmacological Action Anti-Bacterial Agents; Antifungal Agents; Antiviral Agents; Protein Synthesis Inhibitors 		Other names NSC89671; NSC 89671; Synergisidin; NSC-89671; Decumbin; Cyanein; Ascotoxin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
brefeldin A formylate  0   Brefeldin A/*analogs & derivatives. J Asian Nat Prod Res 2009;11(1):54-7
4-oxo-brefeldin A  0   Brefeldin A/*analogs & derivatives. J Org Chem 2002 Jun 14;67(12):4127-37
2,3-dihydro-(2-hydroxypropylthio)brefeldin A  0   Brefeldin A/*analogs & derivatives. J Med Chem 2001 Nov 8;44(23):3915-24
2,3-dihydro-(2-hydroxypropylsulfinyl)brefeldin A  0   Brefeldin A/*analogs & derivatives. J Med Chem 2001 Nov 8;44(23):3915-24
breflate  0   Brefeldin A/*analogs & derivatives. J Pharm Biomed Anal 1998 Apr;16(8):1301-9

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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