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Proto-Oncogene Proteins c-rel

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Definition: Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.     
See Also Genes, rel; I-kappa B Proteins 		Other names rel Proto Oncogene Proteins; rel Proto Oncogene Product p68; p68 c rel; c-rel, p68; c-rel, Proto-Oncogene Proteins; c-rel, Proto-Oncogene Protein; c-rel, Proto-Oncogene Products; c rel Proteins; c rel Protein; Proto-Oncogene Proteins, rel; Proto Oncogene Proteins rel; Proto Oncogene Proteins c rel; Proto Oncogene Protein c rel; Proto Oncogene Products c rel; Proteins, c-rel; Protein, c-rel; rel Proto-Oncogene Product p68; c-rel Protein; Proto-Oncogene Proteins rel; Proto-Oncogene Protein c-rel
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
rel3 protein, Xenopus  0   *Proto-Oncogene Proteins c-rel *Xenopus Proteins. Cell Biol Int. 2004;28(12):895-904

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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