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ras Guanine Nucleotide Exchange Factors

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Definition: A family of GUANINE NUCLEOTIDE EXCHANGE FACTORS that are specific for RAS PROTEINS.     
Examples ras-GRF1; Son of Sevenless Proteins 		Other names ras GEFs; ras GEF; ras-GEFs; ras-GEF; ras Guanine Nucleotide Exchange Factor; rasGEF; rasGEFs
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
RasGEF1B protein, human  0   *ras Guanine Nucleotide Exchange Factors. FEBS J 2009 Aug;276(16):4607-16
Rasgrp2 protein, Xenopus  0   *ras Guanine Nucleotide Exchange Factors *Xenopus Proteins. Biochem Biophys Res Commun 2008 Aug 8;372(4):886-91
RASEF protein, human  0   *ras Guanine Nucleotide Exchange Factors Genes, Tumor Suppressor. Invest Ophthalmol Vis Sci 2008 Apr;49(4):1291-8
RasGRP3 protein, mouse  0   *ras Guanine Nucleotide Exchange Factors. Cancer Res 2008 Jan 1;68(1):64-72
RASGEF1A protein, human  0   *ras Guanine Nucleotide Exchange Factors. Clin Cancer Res 2006 Nov 15;12(22):6611-6
Rasgrf2 protein, rat  0   *ras Guanine Nucleotide Exchange Factors.
Rasgrf2 protein, mouse  0   *ras Guanine Nucleotide Exchange Factors.
RASGRF2 protein, human  0   *ras Guanine Nucleotide Exchange Factors.
Rasgrp4 protein, mouse  0   *ras Guanine Nucleotide Exchange Factors. J Immunol. 2003 Jul 1;171(1):390-7
RASGRP4 protein, human  0   *ras Guanine Nucleotide Exchange Factors. J Biol Chem 2002 Jul 12;277(28):25756-74
RAPGEF5 protein, human  0   *ras Guanine Nucleotide Exchange Factors. J Biol Chem 2000 Nov 10;275(45):34901-8
aimless protein, Dictyostelium  0   *Protozoan Proteins *ras Guanine Nucleotide Exchange Factors. Curr Biol 1996 Jun 1;6(6):719-29

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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