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Plasma Kallikrein

More information in Books or onNLM PubMed
Definition: A peptidohydrolytic enzyme that is formed from PREKALLIKREIN by FACTOR XIIA. It activates FACTOR XII; FACTOR VII; and PLASMINOGEN. It is selective for both ARGININE and to a lesser extent LYSINE bonds. EC 3.4.21.34.     
Pharmacological Action Coagulants 		Other names Kallikrein, Serum; Kallikrein, Plasma; Serum Kallikrein; Kininogenin; Kallikrein I
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PF 04886847  0   *Aminobenzoic Acids *Aminopyridines Plasma Kallikrein/antagonists & inhibitors. Br J Pharmacol 2011 Apr;162(7):1639-49

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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