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Subtilisin

More information in Books or onNLM PubMed
Definition: A serine endopeptidase isolated from Bacillus subtilis. It hydrolyzes proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. It also hydrolyzes peptide amides. (From Enzyme Nomenclature, 1992) EC 3.4.21.62.  SUBTILISINS is also available   
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
protease XXIV  EC 3.4.21.-   *Subtilisin. J Histochem Cytochem 2001 Jul:49(7):923-4
4-boronic acid benzophenone  0   *Benzophenones *Boronic Acids Subtilisin/antagonists & inhibitors. Bioorg Med Chem 2000 Mar;8(3):563-70

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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