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Protein D-Aspartate-L-Isoaspartate Methyltransferase

More information in Books or onNLM PubMed
Definition: A PROTEIN O-METHYLTRANSFERASE that recognizes and catalyzes the methyl esterification of ISOASPARTIC ACID and D-ASPARTIC ACID residues in peptides and proteins. It initiates the repair of proteins damaged by the spontaneous decomposition of normal L-aspartic acid and L-asparagine residues.      Other names Protein beta Aspartate Methyltransferase; Protein Methyltransferase, Isoaspartyl-Aspartyl; Protein L Isoaspartyl Methyltransferase; Protein L Isoaspartate O Methyltransferase; Protein L Isoaspartate Methyltransferase; Protein L Isoaspartate D Aspartate O Methyltransfe; Protein D Aspartate Methyltransferase; Protein D Aspartate L Isoaspartate Methyltransfera; Protein D Asp Methyltransferase; Protein Carboxymethyltransferase, L-Isoaspartyl; PIMT, Methyltransferase; O-Methyltransferase, Protein L-Isoaspartate; Methyltransferase, Protein-beta-Aspartate; Methyltransferase, Protein-L-Isoaspartate; Methyltransferase, Protein-D-Aspartate; Methyltransferase, Protein-D-Asp; Methyltransferase, Protein L-Isoaspartyl; Methyltransferase, Protein D-Aspartate-L-Isoaspart; Methyltransferase, Isoaspartyl-Aspartyl Protein; Methyltransferase, D-Aspartyl-L-Isoaspartyl
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PCMT1 protein, human  EC 2.1.1.77   *Protein D-Aspartate-L-Isoaspartate Methyltransferase. Proc Natl Acad Sci U S A 2001 Aug 28;98(18):10380-5

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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