Definition: A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication.
Other names Topoisomerase IV, DNA; parE Gene Product, Topo IV; parE Gene Product; parC Gene Product, Topo IV; parC Gene Product; Topoisomerase IV Subunit B; Topoisomerase IV Subunit A; Topoisomerase IV; Topo IV; parE Protein; parC Protein