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Pyruvate Dehydrogenase (Lipoamide)

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Definition: The E1 component of the multienzyme PYRUVATE DEHYDROGENASE COMPLEX. It is composed of 2 alpha subunits (pyruvate dehydrogenase E1 alpha subunit) and 2 beta subunits (pyruvate dehydrogenase E1 beta subunit).      Other names Pyruvate Dehydrogenase E1; Pyruvate Dehydrogenase-E1; Pyruvate Dehydrogenase Component E1; Pyruvate Decarboxylase (Lipoamide)
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PDHA2 protein, human  EC 1.2.4.1   *Pyruvate Dehydrogenase (Lipoamide). Mol Genet Metab. 2010 Apr;99(4):425-30
pyruvate dehydrogenase E1 beta subunit  EC 1.2.4.1   *Pyruvate Dehydrogenase (Lipoamide). J Bacteriol 1998 Mar;180(6):1540-8
pyruvate dehydrogenase E1alpha subunit  EC 1.2.4.1   *Pyruvate Dehydrogenase (Lipoamide) Leigh Disease. Nucleic Acids Res 1990;18(16):4925

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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