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Factor For Inversion Stimulation Protein

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Definition: A highly abundant DNA binding protein whose expression is strongly correlated with the growth phase of bacteria. The protein plays a role in regulating DNA topology and activation of RIBOSOMAL RNA transcription. It was originally identified as a factor required for inversion stimulation by the Hin recombinase of SALMONELLA and Gin site-specific recombinase of BACTERIOPHAGE MU.      Other names Inversion Stimulation Factor; HIN Recombinational Enhancer Binding Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Fis protein, E coli  0   *Escherichia coli Proteins *Factor For Inversion Stimulation Protein Transcription Factors. EMBO J. 2004 Aug 18;23(16):3375-85

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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