Definition: A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its rate of degradation is increased in the presence of IRON.
Other names IREB2 Protein; IRE-BP2; RNA-binding protein, IRP-2; IRP 2 RNA binding protein; Iron-Responsive-Element Binding Protein 2; IRP2 Protein; IRP-2 RNA-binding protein
