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Collectins

More information in Books or onNLM PubMed
Definition: A class of C-type lectins that target the carbohydrate structures found on invading pathogens. Binding of collectins to microorganisms results in their agglutination and enhanced clearance. Collectins form trimers that may assemble into larger oligomers. Each collectin polypeptide chain consists of four regions: a relatively short N-terminal region, a collagen-like region, an alpha-helical coiled-coil region, and carbohydrate-binding region.     
Examples Mannose-Binding Lectin; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein D
Other names Lectins, Collagenous; Collectin; Collagenous Lectins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
COLEC12 protein, rat  0   *Collectins *Receptors, Scavenger. Biochim Biophys Acta. 2011 Sep;1810(9):836-42
collectin CL-K1, human  0   *Collectins. Microbiol Immunol 2006;50(12):1001-13
COLEC10 protein, human  0   *Collectins.
COLEC12 protein, human  0   *Collectins *Receptors, Scavenger. Biochem Biophys Res Commun 2001 Feb 2;280(4):1028-35
collectin-43 protein, bovine  156132-72-8   *Collectins. J Biol Chem 1994 Apr 22;269(16):11820-4
conglutinin  0   *Serum Globulins *Collectins Complement Fixation Tests Immunosorbents. Int J Artif Organs 3(1):42;1980

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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