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Cleavage And Polyadenylation Specificity Factor

More information in Books or onNLM PubMed
Definition: An RNA-binding protein that recognizes the AAUAAA RNA SEQUENCE at the 3' end of MRNA. It contains four subunits of 30, 73, 100 and 160 kDa molecular size and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.      Other names Subunit, CPSF-73-kDa; Subunit, CPSF-30-kDa; Subunit, CPSF-160-kDa; Subunit, CPSF-100-kDa; Cleavage Polyadenylation Specificity Factor; Cleavage And Polyadenylation Specificity Factor, 7; Cleavage And Polyadenylation Specificity Factor, 3; Cleavage And Polyadenylation Specificity Factor, 1; Cleavage And Polyadenylation Specificity Factor, 1; CPSF 73 kDa Subunit; CPSF 30 kDa Subunit; CPSF 160 kDa Subunit; CPSF 100 kDa Subunit; Cleavage-Polyadenylation Specificity Factor; Cleavage And Polyadenylation Specificity Factor, 7; Cleavage And Polyadenylation Specificity Factor, 3; Cleavage And Polyadenylation Specificity Factor, 1; Cleavage And Polyadenylation Specificity Factor, 1; CPSF-73-kDa Subunit; CPSF-30-kDa Subunit
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CPSF6 protein, mouse  0   *Cleavage And Polyadenylation Specificity Factor. Biol Reprod 2008 Mar;78(3):472-82
Nudt21 protein, mouse  0   *Cleavage And Polyadenylation Specificity Factor. Biol Reprod 2008 Mar;78(3):472-82
CPSF30 protein, Arabidopsis  0   *Arabidopsis Proteins *Cleavage And Polyadenylation Specificity Factor. Nucleic Acids Res 2007;35(13):4453-63
CPSF73-I protein, Arabidopsis  0   *Arabidopsis Proteins *Cleavage And Polyadenylation Specificity Factor. Plant Mol Biol 2006 Jul;61(4-5):799-815
CPSF73-II protein, Arabidopsis  0   *Arabidopsis Proteins *Cleavage And Polyadenylation Specificity Factor. Gene 2004 Jan 7;324:35-45

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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