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Receptor, TIE-1

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Definition: A TIE receptor found predominantly on ENDOTHELIAL CELLS. It is considered essential for vascular development and can form a heterodimer with the TIE-2 RECEPTOR. The TIE-1 receptor may play a role in regulating BLOOD VESSEL stability and maturation.  see SCR for organism-specific terms    Other names Tyrosine Kinase, TIE1; TIE-1 Receptor; TIE 1 Receptor Tyrosine Kinase; Receptor, TIE 1; TIE1 Tyrosine Kinase; TIE-1 Receptor Tyrosine Kinase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tie1 protein, zebrafish  EC 2.7.1.112   *Zebrafish Proteins Receptor, TIE-1.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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