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Cholestenone 5 alpha-Reductase

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Definition: An oxidoreductase that catalyzes the conversion of compounds that contain 5-alpha-cholestan-3-one into the cholest-4-en-3-one derivative. It plays an important role in the conversion of TESTOSTERONE into DIHYDROTESTOSTERONE and PROGESTERONE into DIHYDROPROGESTERONE.      Other names alpha-Reductase, Cholestenone 5; Cholestenone 5 alpha Reductase; 5 alpha-Reductase, Cholestenone; 5 alpha Reductase; 4 Ene Steroid 5 alpha Reductase; 5 alpha-Reductase; 4-Ene Steroid 5 alpha-Reductase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
AFA76  0   *Fluorobenzenes *Phenanthridines Cholestenone 5 alpha-Reductase/antagonists & inhibitors. J Steroid Biochem Mol Biol 2005 Aug;96(3-4):287-99

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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