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Acyl-CoA Oxidase

More information in Books or onNLM PubMed
Definition: An enzyme that catalyzes the first and rate-determining steps of peroxisomal beta-oxidation of fatty acids. It acts on COENZYME A derivatives of fatty acids with chain lengths from 8 to 18, using FLAVIN-ADENINE DINUCLEOTIDE as a cofactor.      Other names Oxidase, Fatty Acyl-CoA; Oxidase, Acyl-CoA; Fatty Acyl Coenzyme A Oxidase; Fatty Acyl CoA Oxidase; Fatty Acid Acyl CoA Oxidase; Acyl-CoA Oxidase, Fatty; Acyl CoA Oxidase; Fatty Acyl-Coenzyme A Oxidase; Fatty Acyl-CoA Oxidase; Fatty Acid Acyl-CoA Oxidase; Acyl Coenzyme A Oxidase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Peroxisomal ACYL-COA oxidase deficiency  0   *Adrenoleukodystrophy *Lipid Metabolism, Inborn Errors Acyl-CoA Oxidase/deficiency.
oct-2-en-4-ynoyl-coenzyme A  0   *Acyl Coenzyme A Acyl-CoA Oxidase/antagonists & inhibitors. Org Lett 2008 Oct 2;10(19):4287-90
ACX5 protein, Arabidopsis  EC 1.3.3.6   *Arabidopsis Proteins *Acyl-CoA Oxidase. Plant Physiol 2007 Feb;143(2):812-24
ACX2 protein, Arabidopsis  EC 1.3.3.6   *Arabidopsis Proteins *Acyl-CoA Oxidase. Plant J 1999 Oct;20(1):1-13
ACX4 protein, Arabidopsis  EC 1.3.3.6   *Arabidopsis Proteins *Acyl-CoA Oxidase. Acta Crystallogr D Biol Crystallogr 2004 Jun;60(Pt 6):1125-8
ACX1 protein, Arabidopsis  EC 1.3.3.6   *Arabidopsis Proteins *Acyl-CoA Oxidase. Acta Crystallogr D Biol Crystallogr 2004 Jun;60(Pt 6):1125-8
POX1 protein, S cerevisiae  EC 1.3.3.6   *Saccharomyces cerevisiae Proteins *Acyl-CoA Oxidase.
ACX3 protein, Arabidopsis  EC 1.3.3.6   *Arabidopsis Proteins *Acyl-CoA Oxidase. J Biol Chem 2000 Nov 3;275(44):34375-81

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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