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Cytosine Deaminase

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Definition: An enzyme which catalyzes the deamination of CYTOSINE resulting in the formation of URACIL. It can also act on 5-methylcytosine to form THYMIDINE.  see SCR for organism specific terms    Other names Deaminase, Cytosine; Aminohydrolase, Cytosine; Cytosine Aminohydrolase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
APOBEC3 protein, human  EC 3.5.4.1   *Cytosine Deaminase. J Virol 2005 Jul;79(13):8201-7
APOBEC3F protein, human  EC 3.5.4.1   *Cytosine Deaminase. Curr Biol 2004 Aug 10;14(15):1385-91
codA protein, E coli  EC 3.5.4.1   *Escherichia coli Proteins *Cytosine Deaminase. Mol Microbiol 1992 May;6(10):1335-44

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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