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beta-Transducin Repeat-Containing Proteins

More information in Books or onNLM PubMed
Definition: A family of F-box domain proteins that contain sequences that are homologous to the beta subunit of transducin (BETA-TRANSDUCIN). They play an important role in the protein degradation pathway by becoming components of SKP CULLIN F-BOX PROTEIN LIGASES, which selectively act on a subset of proteins including beta-catenin and IkappaBbeta.  see SCR for organism specific terms    Other names beta Transducin Repeat Containing Proteins; beta Transducin Repeat Containing Protein; Repeat-Containing Proteins, beta-Transducin; Repeat-Containing Protein, beta-Transducin; beta TrCP; Protein, beta-Transducin Repeat-Containing; betaTrCP; beta-Transducin Repeat-Containing Protein; beta-TrCP
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Fbxw1b protein, mouse  0   *beta-Transducin Repeat-Containing Proteins Neoplasm Proteins.
beta-TrCP protein, Xenopus  0   *Xenopus Proteins *beta-Transducin Repeat-Containing Proteins.
FBXW11 protein, human  0   *Ubiquitin-Protein Ligases *beta-Transducin Repeat-Containing Proteins. Dev Genet. 1996;19(3):190-8; Oncogene 1999 Mar 25;18(12):2039-46; Oncogene 2002 Feb 28;21(10):1501-9
BTRC protein, human  0   *beta-Transducin Repeat-Containing Proteins.
Btrc protein, mouse  0   *beta-Transducin Repeat-Containing Proteins.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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