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beta-Mannosidase

More information in Books or onNLM PubMed
Definition: An enzyme that catalyzes the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. The enzyme plays a role in the lysosomal degradation of the N-glycosylprotein glycans. Defects in the lysosomal form of the enzyme in humans result in a buildup of mannoside intermediate metabolites and the disease BETA-MANNOSIDOSIS.  /defic: consider also BETA-MANNOSIDOSIS   
See Also beta-Mannosidosis 		Other names beta Mannosidase; beta Mannanase; beta D Mannosidase; manA protein (beta-Mannosidase); beta-Mannanase; beta-D-Mannosidase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Man5 protein, Thermotoga neapolitana  EC 3.2.1.78   *Bacterial Proteins *beta-Mannosidase. Biotechnol Bioeng 2001 Nov 5;75(3):322-33
galactomannanase Man2, Thermotoga neapolitana  EC 3.2.1.25   *Bacterial Proteins *beta-Mannosidase. Biotechnol Bioeng 2001 Nov 5;75(3):322-33

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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