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Transposon Resolvases

More information in Books or onNLM PubMed
Definition: Recombinases that involved in the propagation of DNA TRANSPOSONS. They bind to transposon sequences found at two different sites along the same stretch of DNA and bring them into close proximity. The enzymes then catalyze the double strand cleavage, exchange of double strands and rejoining of DNA helices so that the DNA transposon is formed into a circular PLASMID.  Don't confuse with HOLLIDAY JUNCTION RESOLVASES    Other names TnpR Protein; Resolvases, Transposon
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
gamma delta resolvase  EC 2.7.7.-   *Transposon Resolvases. Nature 1982 Nov 25;300(5890):381-3
Tn3 resolvase  EC 2.7.7.-   *Transposon Resolvases. Gene 2001 May 16;269(1-2):121-30
Tn21 resolvase  EC 2.7.7.-   *Transposon Resolvases.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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