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DNA, Cruciform

More information in Books or onNLM PubMed
Definition: A cross-shaped DNA structure that can be observed under the electron microscope. It is formed by the incomplete exchange of strands between two double-stranded helices or by complementary INVERTED REPEAT SEQUENCES that refold into hairpin loops on opposite strands across from each other.     
See Also G-Quadruplexes; Holliday Junction Resolvases 		Other names Junction, Holliday; Junction DNAs, Holliday; Holliday Junction DNAs; Holliday Junction; DNAs, Holliday Junction; DNAs, Cruciform; DNA, Holliday Junction; DNA Cruciform; Cruciform, DNA; Cruciform DNAs; Holliday Junctions; Holliday Junction DNA; DNA Cruciforms; Cruciform DNA
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
SLX4 protein, human  EC 3.1.-   *Recombinases DNA, Cruciform. Cell 2009 Jul 10;138(1):63-77
cruciform-specific DNA-binding protein, human  0   *DNA-Binding Proteins DNA, Cruciform. Biochemistry 1998 Oct 6;37(40):14317-25; Biochemistry. 1994 Nov 29;33(47):14185-96.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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