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ψ
Cyclotides
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Definition
: A continuous circle of peptide bonds, typically of 2-3 dozen AMINO ACIDS, so there is no free N- or C-terminus. They are further characterized by six conserved CYSTEINE residues that form CYSTINE KNOT MOTIFS.
Substance
CAS Registry & name
Categories
Source
Drugs
*
hedyotide B1
0
*Cyclotides.
Biochemistry. 2011 Aug 23;50(33):7275-83
kalata B2
0
*Cyclotides.
Environ Toxicol Chem. 2011 Aug;30(8):1785-92
kalata B5, Oldenlandia affinis
0
*Cyclotides
Plant Proteins.
Biopolymers. 2010;94(5):647-58
psyle E
0
*Cyclotides.
J Nat Prod. 2010 Jul 23;73(7):1207-13
psyle A
0
*Cyclotides.
J Nat Prod. 2010 Jul 23;73(7):1207-13
psyle C
0
*Cyclotides.
J Nat Prod. 2010 Jul 23;73(7):1207-13
kalata B7, Oldenlandia affinis
0
*Cyclotides.
J Inorg Biochem 2008 May-Jun;102(5-6):1246-56
cycloviolacin O24
0
*Cyclotides.
Biopolymers 2008;90(1):51-60
cycloviolacin O14
0
*Cyclotides.
Biopolymers 2008;90(1):51-60
cycloviolacin O13
0
*Cyclotides.
Biopolymers 2008;90(1):51-60
cycloviolacin Y4
0
*Cyclotides.
J Nat Prod 2008 Jan;71(1):47-52
cycloviolacin Y5
0
*Cyclotides.
J Nat Prod 2008 Jan;71(1):47-52
violacin A
0
*Cyclotides.
J Mol Biol. 2006 Apr 14;357(5):1522-35
cycloviolacin H4
0
*Cyclotides.
J Nat Prod 2006 Jan;69(1):23-8
VHL-
1 protein, Viola hederaceae
0
*Cyclotides.
J Biol Chem 2005 Jun 10;280(23):22395-405
kalata B6
0
*Cyclotides.
Anal Biochem 2005 Feb 1;337(1):149-53
cycloviolacin O2
0
*Cyclotides.
Mol Cancer Ther 2002 Apr;1(6):365-9
varv A
0
*Cyclotides.
Mol Cancer Ther 2002 Apr;1(6):365-9
varv F
0
*Cyclotides.
Mol Cancer Ther 2002 Apr;1(6):365-9
palicourein
0
*Cyclotides.
J Nat Prod 2001 Feb;64(2):249-50
MCoTI-
III protein, Momordica cochinchinensis
0
*Plant Proteins
*Cyclotides.
Biochemistry 2000 May 16;39(19):5722-30
trypsin inhibitor MCoTI-
II
0
*Cyclotides.
Biochemistry 2000 May 16;39(19):5722-30
MCoTI-
I protein, Momordica cochinchinensis
0
*Plant Proteins
*Cyclotides.
Biochemistry 2000 May 16;39(19):5722-30
circulin B
20905-50-4
*Cyclotides.
Biochem Biochem Res Commun 1996 Nov 12;228(2):632-8
circulin A
5854-98-8
*Cyclotides.
Biochem Biochem Res Commun 1996 Nov 12;228(2):632-8
cyclopsychotride A
0
*Cyclotides.
J Nat Prod 1994 Dec;57(12):1619-25
kalata B1
0
*Cyclotides
Rubiaceae
Cystine Knot Motifs.
Protein Sci 1994 Oct;3(10):1833-9
PMP-
C peptide, insect
140880-00-8
*Insect Proteins
*Cyclotides
Nerve Tissue Proteins
Cystine Knot Motifs.
Eur J Biochem 1992 Feb 15;204(1):147-53
PMP-
D2 peptide, insect
140879-98-7
*Cyclotides
*Insect Proteins
Nerve Tissue Proteins
Cystine Knot Motifs.
Eur J Biochem 1992 feb 15;204(1):147-53
circulin
9008-54-2 Circulin
*Cyclotides.
J Chromatogr 112:663;1975