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Mitogen-Activated Protein Kinase 3

More information in Books or onNLM PubMed
Definition: A 44-kDa extracellular signal-regulated MAP kinase that may play a role the initiation and regulation of MEIOSIS; MITOSIS; and postmitotic functions in differentiated cells. It phosphorylates a number of TRANSCRIPTION FACTORS; and MICROTUBULE-ASSOCIATED PROTEINS.      Other names p44mpk, PSTkinase; Mitogen Activated Protein Kinase 3; Microtubule Associated Protein 2 Kinase; MAPK3 Mitogen Activated Protein Kinase; Kinase, Microtubule-Associated Protein-2; Kinase, ERK1; Extracellular Signal Regulated Kinase 1; p44 MAPK; Protein-Serine-Threonine Kinase p44(mpk); Microtubule-Associated Protein-2 Kinase; Meiosis-Activated Myelin Basic Protein Kinase p44(; PSTkinase p44mpk; MAPK3 Mitogen-Activated Protein Kinase; ERK1 Kinase; Extracellular Signal-Regulated Kinase 1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
FR 180204  0   *Pyrazoles *Pyridazines Mitogen-Activated Protein Kinase 1/antagonists & inhibitors Mitogen-Activated Protein Kinase 3/antagonists & inhibitors. Biochem Biophys Res Commun 2005 Oct 14;336(1):357-63
CEK1 protein, Candida albicans  148971-42-0   *Fungal Proteins *Mitogen-Activated Protein Kinase 3. Proc Natl Acad Sci U S A 1992 Oct 15;89(20):9410-4

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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