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X Chromosome Inactivation

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Definition: A dosage compensation process occurring at an early embryonic stage in mammalian development whereby, at random, one X CHROMOSOME of the pair is repressed in the somatic cells of females.      Other names X Inactivations; Inactivation, X Chromosome; Inactivation, X; Hypothesis, Lyon; Chromosome Inactivation, X; X-Inactivation; Lyonization; Lyon Hypothesis; X Inactivation
 
SubstanceCAS Registry & nameCategoriesSource
X (inactive)-specific transcript (XIST)  0   *RNA, Untranslated Dosage Compensation, Genetic X Chromosome X Chromosome Inactivation. Cell 1992 Oct 30;71(3):515-28

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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