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Sodium Chloride Symporters

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Definition: A subclass of symporters found in KIDNEY TUBULES, DISTAL that are the major pathway for salt resorption. Inhibition of these symporters by BENZOTHIADIAZINES is the basis of action of some DIURETICS.  coordinate with DIURETICS if pertinent   
See Also Gitelman Syndrome 		Other names Transporter, Sodium-Chloride; Symporters, Sodium Chloride; Sodium Chloride Transporter; Sodium Chloride Cotransporter; Na Cl Symporters; Cotransporters, Sodium Chloride; Cotransporter, Sodium-Chloride; Chloride Symporters, Sodium; Chloride Cotransporters, Sodium; Sodium-Chloride Transporter; Sodium-Chloride Cotransporter; Sodium Chloride Cotransporters; Na-Cl-Symporters
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
SLC12A10.2 protein, zebrafish  0   *Zebrafish Proteins *Sodium Chloride Symporters. Am J Physiol Regul Integr Comp Physiol 2009 May;296(5):R1650-60
thiazide receptor  0   *Receptors, Drug *Sodium Chloride Symporters. Clin Exp Hypertens (A) 1990;12(2):215; J Am Soc Nephrol. 2003 Feb;14(2):538-40

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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