Core Binding Factors (definition)

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ψ	Core Binding Factors

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Definition: Heterodimeric transcription factors containing a DNA-binding alpha subunits, (CORE BINDING FACTOR ALPHA SUBUNITS), along with a non-DNA-binding beta subunits, CORE BINDING FACTOR BETA SUBUNIT. Core Binding Factor regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression.

see SCR for organism-specific terms
Examples Core Binding Factor alpha Subunits; Core Binding Factor beta Subunit

Other names Transcription Factor, PEBP2; Factors, Core Binding; Core Binding Factor; Binding Factors, Core; Polyomavirus Enhancer Binding Protein 2; PEBP2 Transcription Factor; Core-Binding Factor

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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