encyclopedia of medical concepts
ψ 

E2F Transcription Factors

More information in Books or onNLM PubMed
Definition: A family of basic helix-loop-helix transcription factors that control expression of a variety of GENES involved in CELL CYCLE regulation. E2F transcription factors typically form heterodimeric complexes with TRANSCRIPTION FACTOR DP1 or transcription factor DP2, and they have N-terminal DNA binding and dimerization domains. E2F transcription factors can act as mediators of transcriptional repression or transcriptional activation.     
Examples E2F1 Transcription Factor; E2F2 Transcription Factor; E2F3 Transcription Factor; E2F4 Transcription Factor; E2F5 Transcription Factor; E2F6 Transcription Factor; E2F7 Transcription Factor 		Other names Transcription Factors, E2F; E2F, Transcription Factor; Transcription Factor E2F; E2F Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
E2FC protein, Arabidopsis  0   *Arabidopsis Proteins *E2F Transcription Factors. J Biol Chem 2002 Mar 22;277(12):9911-9
E2Fb protein, Arabidopsis  0   *Arabidopsis Proteins *E2F Transcription Factors. FEBS Lett 2000 Dec 1;486(1):79-87
E2Fa protein, Arabidopsis  0   *Arabidopsis Proteins *E2F Transcription Factors Cell Cycle Proteins. FEBS Lett 2000 Dec 1;486(1):79-87
efl-1 protein, C elegans  0   *Caenorhabditis elegans Proteins *E2F Transcription Factors.
E2F protein, Drosophila  0   *Drosophila Proteins *E2F Transcription Factors. Nucleic Acids Res 2002 Dec 1;30(23):5029-35
E2L2 protein, Arabidopsis  0   *Repressor Proteins *Arabidopsis Proteins *E2F Transcription Factors. J Biol Chem 2002 May 10;277(19):16553-8

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy