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Cyclin-Dependent Kinase Inhibitor p27

More information in Books or onNLM PubMed
Definition: A cyclin-dependent kinase inhibitor that coordinates the activation of CYCLIN and CYCLIN-DEPENDENT KINASES during the CELL CYCLE. It interacts with active CYCLIN D complexed to CYCLIN-DEPENDENT KINASE 4 in proliferating cells, while in arrested cells it binds and inhibits CYCLIN E complexed to CYCLIN-DEPENDENT KINASE 2.     
Pharmacological Action Protein Kinase Inhibitors 		Other names p27, CDK Inhibitor; Kip1 Protein, p27; Cyclin Dependent Kinase Inhibitor p27; Cyclin Dependent Kinase Inhibitor 1B; CDK Inhibitor, p27; p27Kip1 Protein; p27 Kip1 Protein; p27 CDK Inhibitor; Cyclin-Dependent Kinase Inhibitor 1B; CDKN4 Protein; CDKN1B Protein; CDK Inhibitor p27
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Xicl protein, Xenopus  0   *Xenopus Proteins *Cyclin-Dependent Kinase Inhibitor p27.
Cdkn1b protein, rat  0   *Cyclin-Dependent Kinase Inhibitor p27.
Cdkn1b protein, mouse  0   *Cyclin-Dependent Kinase Inhibitor p27.
CDKN1B protein, human  0   *Cyclin-Dependent Kinase Inhibitor p27 Cyclin-Dependent Kinase Inhibitor p27. Plant Physiol 2001 Aug;126(4):1480-92

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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