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p300-CBP Transcription Factors

More information in Books or onNLM PubMed
Definition: A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION.     
Examples CREB-Binding Protein; E1A-Associated p300 Protein 		Other names p300 CBP Transcription Factors; p300 CBP Protein; p300 CBP Coactivator; Transcription Factors, p300-CBP; Coactivator, p300-CBP; p300-CBP Protein; p300-CBP Coactivator
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
nejire protein, Drosophila  0   *Drosophila Proteins *p300-CBP Transcription Factors. J Biol Chem 2007 Oct 26;282(43):31349-57
p300-CBP-associated factor  EC 2.3.1.48   *p300-CBP Transcription Factors. Nature 1996 Jul 25;382(6589):319-24

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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